What It Is
PT-141 (Bremelanotide) is a melanocortin-4 receptor agonist derived from α-MSH. Unlike systemic approaches, it acts directly on the central nervous system to promote sexual arousal and desire through melanocortin signalling pathways.
How It Works
PT-141 crosses the blood-brain barrier and binds to MC4 receptors in the brain's hypothalamus, the region responsible for sexual arousal and motivation. This central nervous system action triggers dopamine release and pro-sexual signalling, independent of vascular or peripheral mechanisms.
Key Benefits & Use Cases
- Enhanced sexual arousal and desire
- Support for sexual motivation and response
- Direct CNS action without vascular dependency
- Research into melanocortin signalling and behaviour
General Dosage Information
Research protocols typically use 0.5-1.0mg administered 2-3 hours before the desired effect. Doses can be repeated up to daily use. Effects typically appear within 15-30 minutes.
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